Which bronchodilator reversibility criteria can predict severe acute exacerbation in chronic obstructive pulmonary disease patients?

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Which bronchodilator reversibility criteria can predict severe acute exacerbation in chronic obstructive pulmonary disease patients?

BACKGROUND It is unclear whether various bronchodilator reversibility (BDR) criteria affect the prognosis of chronic obstructive pulmonary disease (COPD). The aim of this study is to evaluate the impact of positive BDR defined according to various BDR criteria on the risk of severe acute exacerbation (AE) in COPD patients. METHODS Patients from four prospective COPD cohorts in South Korea who...

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CHRONIC OBSTRUCTIVE PULMONARY DISEASE Bronchodilator reversibility testing in chronic obstructive pulmonary disease

Background: A limited or absent bronchodilator response is used to classify chronic obstructive pulmonary disease (COPD) and can determine the treatment offered. The reliability of the recommended response criteria and their relationship to disease progression has not been established. Methods: 660 patients meeting European Respiratory Society (ERS) diagnostic criteria for irreversible COPD wer...

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Comparing Serum Procalcitonin Levels Between Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease and Patients with Acute Exacerbation of Asthma

Background and purpose: Serum procalcitonin (PCT) indicates a bacterial infection that can reduce the administration of antibiotics. The aim of this study was to compare serum procalcitonin levels in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) and asthma and its relationship with lung function and inflammatory factors. Materials and methods: In this cross-s...

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[Acute exacerbation of chronic obstructive pulmonary disease].

Exacerbation of COPD is a common problem, which causes a considerable burden to the patient and the healthcare system. Management of exacerbations is broadly based on clinical features and severity. Initial clinical evaluation is crucial to define the patients requiring hospital admissions and those that could be managed as outpatients. Medical treatment should follow updated recommendations in...

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ژورنال

عنوان ژورنال: Respiratory Research

سال: 2017

ISSN: 1465-993X

DOI: 10.1186/s12931-017-0587-9